Antimicrobial-resistant Pathogens in the 1990s

Annu Rev Med. 1996;47:169-79. doi: 10.1146/annurev.med.47.1.169.

Abstract

Streptococcus pneumoniae, Enterococcus faecalis, Enterococcus faecium, Staphylococcus aureus, and Klebsiella pneumoniae have become increasingly resistant to antimicrobial agents. This chapter reviews the epidemiology of this resistance, its detection in the laboratory, the mechanisms of resistance, and the options for therapy and infection control.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / adverse effects
  • Anti-Bacterial Agents / therapeutic use*
  • Bacterial Infections / drug therapy*
  • Bacterial Infections / microbiology
  • Dose-Response Relationship, Drug
  • Drug Resistance, Microbial / genetics
  • Drug Resistance, Multiple / genetics
  • Enterococcus faecalis / drug effects*
  • Enterococcus faecalis / genetics
  • Enterococcus faecium / drug effects*
  • Enterococcus faecium / genetics
  • Humans
  • Klebsiella pneumoniae / drug effects*
  • Klebsiella pneumoniae / genetics
  • Microbial Sensitivity Tests
  • Staphylococcus aureus / drug effects*
  • Staphylococcus aureus / genetics
  • Streptococcus pneumoniae / drug effects*
  • Streptococcus pneumoniae / genetics

Substances

  • Anti-Bacterial Agents