Review
doi: 10.1038/icb.1995.79.
The ecology and pathology of Epstein-Barr virus
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- PMID: 8713470
- DOI: 10.1038/icb.1995.79
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Review
The ecology and pathology of Epstein-Barr virus
Immunol Cell Biol.
1995 Dec.
Abstract
Epstein-Barr virus achieves its ubiquitous and uniform epidemiological distribution by a dual strategy of latency to guarantee lifelong persistence and intermittent replication to guarantee transmission. These two functions appear to dictate residence in different cell types: latency in B lymphocytes and replication in epithelial cells. Both of these cell compartments are potential sites for EBV-associated malignancies.
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