[The dynamics of cardiac vagal sinus arrhythmia in cats under the action of met-enkephalin]

Fiziol Zh Im I M Sechenova. 1995 Jul;81(7):69-73.
[Article in Russian]


When stimulating the peripheral and of the right n. vagus in anesthetised cats, the sinus arrhythmia occurred in case the vagal bursts were beyond the limits of the controlled bradycardia range. I. v. administration of met-enkephaline suppressed the arrhythmia immediately but the latter reappeared within 15-20 minutes. The data obtained suggests a biphasic effect of met-enkephaline upon the vagal sinus arrhythmia.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Arrhythmia, Sinus / physiopathology*
  • Cats
  • Electric Stimulation
  • Electrocardiography / drug effects
  • Enkephalin, Methionine / pharmacology*
  • Heart Rate / drug effects
  • Heart Rate / physiology
  • Time Factors
  • Vagus Nerve / physiology*


  • Enkephalin, Methionine