Systemic hypersensitivity reaction to intravesical BCG

Scott Med J. 1994 Apr;39(2):49-50. doi: 10.1177/003693309403900205.

Abstract

BCGosis is a recognised complication of intravesical BCG immunotherapy for superficial bladder carcinoma. We present here a case of granulomatous hepatitis, pneumonitis and probable pericarditis resulting from an hypersensitivity reaction to intravesical BCG.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Alveolitis, Extrinsic Allergic / etiology
  • Alveolitis, Extrinsic Allergic / pathology
  • BCG Vaccine / administration & dosage
  • BCG Vaccine / adverse effects*
  • Carcinoma, Transitional Cell / surgery
  • Carcinoma, Transitional Cell / therapy*
  • Drug Hypersensitivity / etiology*
  • Drug Hypersensitivity / physiopathology
  • Hepatitis / etiology
  • Hepatitis / pathology
  • Humans
  • Hypersensitivity, Immediate / chemically induced*
  • Hypersensitivity, Immediate / physiopathology
  • Injections, Intralesional
  • Male
  • Pericarditis / etiology
  • Pericarditis / pathology
  • Urinary Bladder Neoplasms / surgery
  • Urinary Bladder Neoplasms / therapy*

Substances

  • BCG Vaccine