Abstract
Twenty-three patients with chronic idiopathic urticaria and 3 patients with urticaria pigmentosa received a 2-week treatment with daily application of potent topical steroid using plastic occlusion. Seventy per cent of the chronic urticaria patients had a statistically significant, immediate response, which, however, did not last until the final evaluation after 1.5 years. Relapse occurred after on average 3 weeks, but 39% reported less severity. The 3 patients with urticaria pigmentosa remained free from attacks for 6 to 9 months, after which they gradually relapsed. Two women were diagnosed during the follow-up period to have a carcinoma of the breast, and one patient developed systemic lupus erythematosus.
MeSH terms
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Administration, Topical
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Adolescent
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Adult
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Anti-Inflammatory Agents / administration & dosage
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Anti-Inflammatory Agents / therapeutic use*
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Breast Neoplasms / etiology
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Breast Neoplasms / pathology
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Chronic Disease
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Clobetasol / administration & dosage
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Clobetasol / analogs & derivatives*
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Clobetasol / therapeutic use
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Female
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Follow-Up Studies
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Glucocorticoids
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Humans
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Lupus Erythematosus, Systemic / etiology
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Lupus Erythematosus, Systemic / pathology
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Male
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Middle Aged
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Occlusive Dressings
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Recurrence
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Retrospective Studies
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Single-Blind Method
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Surveys and Questionnaires
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Treatment Outcome
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Urticaria / complications
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Urticaria / drug therapy*
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Urticaria / pathology
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Urticaria Pigmentosa / complications
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Urticaria Pigmentosa / drug therapy*
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Urticaria Pigmentosa / pathology
Substances
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Anti-Inflammatory Agents
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Glucocorticoids
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Clobetasol