Treatment of chronic idiopathic urticaria with topical steroids. An open trial

Acta Derm Venereol. 1996 Jan;76(1):43-4. doi: 10.2340/00015555764344.

Abstract

Twenty-three patients with chronic idiopathic urticaria and 3 patients with urticaria pigmentosa received a 2-week treatment with daily application of potent topical steroid using plastic occlusion. Seventy per cent of the chronic urticaria patients had a statistically significant, immediate response, which, however, did not last until the final evaluation after 1.5 years. Relapse occurred after on average 3 weeks, but 39% reported less severity. The 3 patients with urticaria pigmentosa remained free from attacks for 6 to 9 months, after which they gradually relapsed. Two women were diagnosed during the follow-up period to have a carcinoma of the breast, and one patient developed systemic lupus erythematosus.

Publication types

  • Clinical Trial

MeSH terms

  • Administration, Topical
  • Adolescent
  • Adult
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use*
  • Breast Neoplasms / etiology
  • Breast Neoplasms / pathology
  • Chronic Disease
  • Clobetasol / administration & dosage
  • Clobetasol / analogs & derivatives*
  • Clobetasol / therapeutic use
  • Female
  • Follow-Up Studies
  • Glucocorticoids
  • Humans
  • Lupus Erythematosus, Systemic / etiology
  • Lupus Erythematosus, Systemic / pathology
  • Male
  • Middle Aged
  • Occlusive Dressings
  • Recurrence
  • Retrospective Studies
  • Single-Blind Method
  • Surveys and Questionnaires
  • Treatment Outcome
  • Urticaria / complications
  • Urticaria / drug therapy*
  • Urticaria / pathology
  • Urticaria Pigmentosa / complications
  • Urticaria Pigmentosa / drug therapy*
  • Urticaria Pigmentosa / pathology

Substances

  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Clobetasol