Clonazepam for the treatment of lancinating phantom limb pain

Clin J Pain. 1996 Mar;12(1):59-62. doi: 10.1097/00002508-199603000-00011.

Abstract

Objective: To propose clonazepam for use in the empiric treatment of shooting/shocking phantom limb pain.

Setting: Outpatient pain clinic associated with a university hospital.

Patients: Two patients with phantom limb pain after total hip disarticulation.

Interventions: Treatment with clonazepam.

Results and conclusions: Clonazepam provided effective relief for > 6 months in two patients with shooting/shocking phantom limb pain. Although clonazepam therapy is not new, it appears to have been omitted from current pain texts and journals as a treatment option for phantom limb pain.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Amitriptyline / therapeutic use
  • Antidepressive Agents, Tricyclic / therapeutic use
  • Clonazepam / therapeutic use*
  • Disarticulation / adverse effects
  • Drug Therapy, Combination
  • Female
  • Femoral Neoplasms / surgery
  • GABA Modulators / therapeutic use*
  • Humans
  • Middle Aged
  • Osteosarcoma / surgery
  • Pain / drug therapy*
  • Pain / etiology
  • Phantom Limb / drug therapy*

Substances

  • Antidepressive Agents, Tricyclic
  • GABA Modulators
  • Amitriptyline
  • Clonazepam