Coexistence of multiple perifollicular fibromas and colonic polyp and cancer

Dermatology. 1996;192(3):262-3. doi: 10.1159/000246380.


Perifollicular fibroma (PFF) is a rare cutaneous hamartoma that shows differentiation to the connective tissue sheath of the hair follicle. It may be solitary or multiple; the latter has been suggested to exhibit autosomal dominant inheritance and association with colonic polyposis. We report a 72-year-old Japanese female with multiple PFF on the face, possibly familial, who developed colon cancer in addition to colonic polyps.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma / complications
  • Adenocarcinoma / pathology
  • Aged
  • Colonic Neoplasms / complications*
  • Colonic Neoplasms / pathology
  • Colonic Polyps / complications
  • Colonic Polyps / pathology
  • Female
  • Hamartoma / complications*
  • Hamartoma / pathology
  • Humans
  • Nose
  • Skin Neoplasms / complications*
  • Skin Neoplasms / pathology