Iron acquisition in the pathogenic Neisseria

Trends Microbiol. 1996 May;4(5):179-84. doi: 10.1016/0966-842x(96)10029-9.

Abstract

Pathogenic Neisseria species need to obtain iron from the host to grow in vivo. Several iron-transport systems are known, and regulation of Neisseria iron-transport genes occurs via the transcriptional regulator Fur. There is evidence that the ability to transport iron is crucial to the survival of these organisms in vivo.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Bacterial Outer Membrane Proteins / physiology
  • Base Sequence
  • Biological Transport
  • Gene Expression Regulation, Bacterial
  • Humans
  • Iron / metabolism*
  • Molecular Sequence Data
  • Neisseria / metabolism*
  • Neisseria / pathogenicity

Substances

  • Bacterial Outer Membrane Proteins
  • Iron