A benzoic acid glycoside from Geniostoma antherotrichum

Phytochemistry. 1996 Mar;41(4):1205-7. doi: 10.1016/0031-9422(95)00768-7.

Abstract

Fractionation of an HIV-inhibitory organic extract of Geniostoma antherotrichum afforded a glycoside derivative, which has been characterized as 2-hydroxy-3-O-beta-D-glucopyranosyl-benzoic acid (1) on the basis of spectral analyses. The HIV-inhibitory activity of the extract was traced to polymeric tannins, while 1 was found to be inactive in the National Cancer Institute's primary anti-HIV screen.

MeSH terms

  • Antiviral Agents / chemistry
  • Antiviral Agents / isolation & purification*
  • Glucosides / chemistry
  • Glucosides / isolation & purification*
  • HIV / drug effects
  • Plants / chemistry*
  • Salicylates / chemistry
  • Salicylates / isolation & purification*
  • Spectrum Analysis

Substances

  • 2-hydroxy-3-O-glucopyranosylbenzoic acid
  • Antiviral Agents
  • Glucosides
  • Salicylates