Scavenger receptors in innate immunity

Curr Opin Immunol. 1996 Feb;8(1):20-8. doi: 10.1016/s0952-7915(96)80100-2.


Scavenger receptors are cell-surface proteins expressed by mammalian monocytes and macrophages and by invertebrate hemocytes, among other cell types. They exhibit distinctive ligand-binding properties, recognizing a wide range of ligands that include microbial surface constituents and intact microbes. The ligand-binding properties and expression patterns of these receptors suggest that they may function in one or more host-defense-related processes. Significant advances in scavenger receptor biology have recently been reported, including the identification of several new scavenger receptor genes.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Apoptosis
  • Hemocytes / chemistry*
  • Hemocytes / immunology
  • Immunity, Innate*
  • Macrophages / chemistry*
  • Macrophages / immunology
  • Models, Molecular
  • Monocytes / chemistry*
  • Monocytes / immunology
  • Receptors, Cell Surface* / classification
  • Receptors, Cell Surface* / immunology
  • Receptors, Cell Surface* / physiology
  • Wound Healing


  • Receptors, Cell Surface