Saccharomyces Cerevisiae TEC1 Is Required for Pseudohyphal Growth

Mol Microbiol. 1996 Mar;19(6):1255-63. doi: 10.1111/j.1365-2958.1996.tb02470.x.

Abstract

Diverse eukaryotic organisms share developmental transcription factors with homologous DNA-binding domains. We showed that the developmental regulator AbaA, a member of the ATTS/TEA (AbaA, TEF-1, TEC1, Scalloped/TEF-1, TEC1, AbaA) class of transcription factors of the filamentous fungus Aspergillus nidulans, induces pseudohyphal development in the yeast Saccharomyces cerevisiae. The S. cerevisiae homologue of AbaA, TEC1p, is required for this morphological transition. We provide evidence that TEC1p functions in co-operation with STE12p to induce pseudohyphal development.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Aspergillus nidulans / genetics
  • Base Sequence
  • Binding Sites / genetics
  • DNA, Fungal / genetics
  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / physiology*
  • Fungal Proteins / genetics
  • Fungal Proteins / physiology*
  • Genes, Fungal
  • Molecular Sequence Data
  • Mutation
  • Phenotype
  • Saccharomyces cerevisiae / genetics
  • Saccharomyces cerevisiae / growth & development*
  • Saccharomyces cerevisiae / physiology*
  • Saccharomyces cerevisiae Proteins*
  • Suppression, Genetic
  • Transcription Factors / genetics
  • Transcription Factors / physiology*
  • Transformation, Genetic

Substances

  • DNA, Fungal
  • DNA-Binding Proteins
  • Fungal Proteins
  • Saccharomyces cerevisiae Proteins
  • TEC1 protein, S cerevisiae
  • Transcription Factors

Associated data

  • GENBANK/J04850
  • GENBANK/M32797
  • GENBANK/M63896
  • GENBANK/M83787