The prognostic value of blood glucose in diabetic patients with acute myocardial infarction

Diabet Med. 1996 Jan;13(1):80-3. doi: 10.1002/(SICI)1096-9136(199601)13:1<80::AID-DIA10>3.0.CO;2-W.

Abstract

The aim of the study was to investigate prospectively the prognostic value of blood glucose on admission in diabetic and non-diabetic patients with an acute myocardial infarction. Three hundred and thirty-three diabetic and 565 non-diabetic patients were admitted with acute myocardial infarction during the study period of 3.5 years. There was a significant association between mortality and blood glucose on admission in diabetic patients (regression coefficient, r = 0.92, 0.5 < p < 0.02) but not in non-diabetic individuals (r = 0.69, 0.2 < p < 0.5). Age- and sex-standardized mortality was higher in the diabetic group (12.2% vs 7.4%, p < 0.03), but was identical if standardized also for blood glucose on admission. We conclude that a high blood glucose on admission is a bad prognostic indicator in a diabetic patient with an acute myocardial infarction. The excess mortality in diabetic patients with acute myocardial infarction can be attributed to the higher proportion with hyperglycaemia.

Publication types

  • Comparative Study

MeSH terms

  • Aspartate Aminotransferases / blood
  • Blood Glucose / analysis*
  • Creatine Kinase / blood
  • Diabetes Complications
  • Diabetes Mellitus / blood*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / blood*
  • Myocardial Infarction / complications
  • Myocardial Infarction / mortality*
  • Odds Ratio
  • Predictive Value of Tests
  • Prognosis
  • Regression Analysis
  • Survival Rate

Substances

  • Blood Glucose
  • Aspartate Aminotransferases
  • Creatine Kinase