PROMOTIF--a program to identify and analyze structural motifs in proteins

Protein Sci. 1996 Feb;5(2):212-20. doi: 10.1002/pro.5560050204.


We describe a suite of programs, PROMOTIF, that analyzes a protein coordinate file and provides details about the structural motifs in the protein. The program currently analyzes the following structural features: secondary structure; beta-and gamma-turns; helical geometry and interactions; beta-strands and beta-sheet topology; beta-bulges; beta-hairpins; beta-alpha-beta units and psi-loops; disulphide bridges; and main-chain hydrogen bonding patterns. PROMOTIF creates postscript files showing the examples of each type of motif in the protein, and a summary page. The program can also be used to compare motifs in a group of related structures, such as an ensemble of NMR structures.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence*
  • Cystine / chemistry*
  • Hydrogen Bonding*
  • Magnetic Resonance Spectroscopy
  • Protein Structure, Secondary*
  • Software*


  • Cystine