Causes of increased renal medullary echogenicity in Turkish children

Pediatr Nephrol. 1995 Dec;9(6):729-33. doi: 10.1007/BF00868724.


The primary disorders of 50 children with increased renal medullary echogenicity on renal ultrasound were studied; 28 girls and 22 boys aged from 1 month to 16 years were classified into four groups based on underlying disease and ultrasound findings. Group 1 was composed of 17 patients with distal renal tubular acidosis (34%); intense echoes throughout the pyramid were predominant. Group 2 consisted of 14 patients with vitamin D toxicity (28%) and an intense echogenic rim around the pyramids. Group 3 included 10 patients with different types of tubulopathies. A slight hyperechogenic rim around the sides and tip of the medullary pyramids was detected. Group 4 was made up of 9 patients with rare underlying conditions. Abdominal X-rays detected medullary calcinosis in only 12 (24%) of the total 50 patients. Ultrasonography appears to be an important tool in the early diagnosis of increased renal medullary echogenicity and medullary nephrocalcinosis.

Publication types

  • Clinical Trial

MeSH terms

  • Acidosis, Renal Tubular / diagnostic imaging
  • Adolescent
  • Calcium / urine
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Kidney Calculi / diagnostic imaging
  • Kidney Diseases / diagnostic imaging*
  • Kidney Diseases / etiology
  • Kidney Medulla / diagnostic imaging*
  • Kidney Tubules / diagnostic imaging
  • Male
  • Nephrocalcinosis / diagnostic imaging*
  • Radiography
  • Turkey
  • Ultrasonography
  • Vitamin D / adverse effects


  • Vitamin D
  • Calcium