Inferring population history from molecular phylogenies

Philos Trans R Soc Lond B Biol Sci. 1995 Jul 29;349(1327):25-31. doi: 10.1098/rstb.1995.0087.


Variable molecular sequences sampled from a population can be used to infer its dynamic history. Graphical methods are developed and applied to real data, illustrating ways of navigating through hypothesis space with two landmarks for reference: constant population size and exponentially growing population size.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genetics, Population*
  • Genome, Viral
  • Humans
  • Mathematics
  • Mitochondria / genetics
  • Molecular Biology
  • Phylogeny*
  • Sequence Analysis, DNA
  • Time Factors