Effects of age, sex, and heredity on measures of bone mass in baboons (Papio hamadryas)

J Med Primatol. 1995 Dec;24(4):236-42. doi: 10.1111/j.1600-0684.1995.tb00176.x.

Abstract

Bone mass and bone density were estimated in 219 pedigreed baboons (Papio hamadryas) by radiographic morphometry of the left second metacarpal. Compact bone width (total bone width--medullary canal diameter) and bone ratio (compact bone width/total bone width) decreased with increasing age squared in both sexes. The heritability of medullary canal diameter was 0.64 +/- 0.11, of compact bone width was 0.40 +/- 0.15 and of bone ratio was 0.67 +/- 0.13. The results indicate baboons are a useful model for studies of age, sex and genetic effects on bone mass.

Publication types

  • Comparative Study

MeSH terms

  • Aging / physiology*
  • Animals
  • Blood Pressure
  • Body Weight
  • Bone Density*
  • Bone Development
  • Bone and Bones / anatomy & histology*
  • Bone and Bones / diagnostic imaging
  • Female
  • Male
  • Metacarpus / anatomy & histology*
  • Metacarpus / diagnostic imaging
  • Metacarpus / growth & development
  • Papio / anatomy & histology*
  • Papio / genetics
  • Probability
  • Radiography
  • Regression Analysis
  • Sex Characteristics