Orbital presentation of ethmoid sinus adenocarcinoma

Acta Ophthalmol Scand. 1995 Oct;73(5):457-9. doi: 10.1111/j.1600-0420.1995.tb00309.x.


Ethmoid sinus adenocarcinoma with orbital invasion is distinctly uncommon. This case presented with epiphora, whereas proptosis and decreased ocular motility were later signs. Treatment was delayed for 4 months, while misdiagnoses like dacryocystitis and thyroid eye disease were entertained. Even an incisional biopsy was not sufficient for a conclusive diagnosis and adenomatous differentiation was only present in a small proportion of tissue available after an excisional attempt. The aggressive behaviour including this patient's death of metastatic disease, underlines the importance of considering secondary invasion from a sino-nasal malignancy in uncharacteristic orbital disease.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / secondary*
  • Adult
  • Diplopia / diagnosis
  • Ethmoid Sinus / pathology*
  • Fatal Outcome
  • Female
  • Humans
  • Lacrimal Apparatus Diseases / diagnosis
  • Magnetic Resonance Imaging
  • Neoplasm Invasiveness
  • Ocular Motility Disorders / diagnosis
  • Orbital Neoplasms / secondary*
  • Paranasal Sinus Neoplasms / pathology*