Follow-up of coil occlusion of patent ductus arteriosus

J Am Coll Cardiol. 1996 Jul;28(1):207-11. doi: 10.1016/0735-1097(96)00107-6.


Objective: We sought to determine the prevalence and fate of residual ductal shunting following coil occlusion of patent ductus arteriosus.

Background: Although transcatheter coil occlusion of patent ductus arteriosus has gained popularity, few follow-up data have been reported.

Methods: A review of 75 patients who underwent coil occlusion was performed. Residual shunting was investigated by Doppler echocardiography in follow-up. Angiograms were reviewed to obtain minimal ductal diameter and ductal angiographic type.

Results: Residual shunts were found in 31 patients (41%) on the day of the procedure, and of these, spontaneous closure was noted in 17 (55%) at 2 weeks to 20 months of follow-up. Of the 75 patients studied, 5 (7%) required a second coil procedure, and 10 (13%) remained with persistent residual shunts at most recent follow-up. Actuarial analysis estimated a 6 +/- 5% prevalence of residual shunts 20 months after a single coil procedure and 3 +/- 3% after all coil procedures. Minimal ductal diameter was associated with immediate complete ductal occlusion by a single coil. These patients had significantly smaller (p = 0.003) minimal ductal diameters (1.2 +/- 0.7 mm) than those who required two coils during their initial procedure to achieve immediate occlusion (1.9 +/- 0.7 mm), those who required a second coil procedure (2.0 +/- 0.9 mm), those who had spontaneous closure of residual shunts (1.9 +/- 0.7 mm) and those with persistent residual shunts (2.0 +/- 0.9 mm). No association was identified between ductal angiographic type and outcome of coil occlusion. No late adverse clinical events of coil occlusion or evidence of recanalization was found.

Conclusions: Small residual shunts are common after coil embolization of patent ductus arteriosus, but most close spontaneously. Actuarial analysis estimates complete closure in 94% at 20 months, and reintervention was required in only 7% of patients.

MeSH terms

  • Actuarial Analysis
  • Child, Preschool
  • Ductus Arteriosus, Patent / diagnosis
  • Ductus Arteriosus, Patent / epidemiology
  • Ductus Arteriosus, Patent / therapy*
  • Echocardiography, Doppler, Color
  • Embolization, Therapeutic*
  • Follow-Up Studies
  • Humans
  • Prevalence
  • Time Factors
  • Treatment Outcome