A malariometric survey in Turkana District, Kenya: chemosensitivity in vivo of Plasmodium falciparum infections and identity of the vector

Trans R Soc Trop Med Hyg. May-Jun 1996;90(3):302-4. doi: 10.1016/s0035-9203(96)90262-x.

Abstract

We have carried out a limited survey in vivo of the efficacy of chloroquine (n = 39) and pyrimethamine-sulfadoxine (n = 29) as treatments for falciparum malaria in Kaling, Turkana District, northern Kenya. Both treatments were effective, achieving clinical cure (> 75% reduction in parasitaemia on day 2 with clinical improvement, and negative blood slide on day 7) in both children and adults. A limited entomological survey suggested that the main malaria vector in this area was Anopheles arabiensis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Anopheles / classification
  • Anopheles / parasitology
  • Antimalarials / therapeutic use
  • Child
  • Child, Preschool
  • Chloroquine / therapeutic use
  • Drug Combinations
  • Drug Resistance
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Insect Vectors
  • Kenya
  • Malaria, Falciparum / drug therapy*
  • Male
  • Parasitemia / drug therapy
  • Pyrimethamine / therapeutic use
  • Sulfadoxine / therapeutic use
  • Treatment Outcome

Substances

  • Antimalarials
  • Drug Combinations
  • fanasil, pyrimethamine drug combination
  • Sulfadoxine
  • Chloroquine
  • Pyrimethamine