A developmental stage-specific histone H1 homolog of Coxiella burnetii

J Bacteriol. 1996 Aug;178(16):5049-52. doi: 10.1128/jb.178.16.5049-5052.1996.

Abstract

Two DNA-binding proteins have been detected in Coxiella burnetii by southwestern (DNA-protein) blotting. One of these, termed Hq1, is enriched in the small cell variant stage of the developmental cycle and displays compositional and primary amino acid sequence similarities to eukaryotic histone H1. C. burnetii appears to be another example of an intracellular parasite with morphologically distinct developmental forms whose nucleoid structure may be controlled by histone H1 homologs.

Publication types

  • Comparative Study

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Centrifugation, Density Gradient
  • Cloning, Molecular
  • Coxiella burnetii / metabolism
  • Coxiella burnetii / physiology*
  • DNA-Binding Proteins / biosynthesis*
  • DNA-Binding Proteins / chemistry*
  • DNA-Binding Proteins / isolation & purification
  • Electrophoresis, Polyacrylamide Gel
  • Histones / chemistry*
  • Molecular Sequence Data
  • Recombinant Proteins / biosynthesis
  • Recombinant Proteins / chemistry
  • Recombinant Proteins / isolation & purification
  • Sequence Homology, Amino Acid

Substances

  • DNA-Binding Proteins
  • Histones
  • Recombinant Proteins

Associated data

  • GENBANK/L79945