Association Between Antifol Resistance in Vitro and DHFR Gene Point Mutation in Plasmodium Falciparum Isolates

Trans R Soc Trop Med Hyg. Mar-Apr 1996;90(2):181-2. doi: 10.1016/s0035-9203(96)90130-3.

MeSH terms

  • Animals
  • Antimalarials / pharmacology
  • Drug Resistance
  • Folic Acid Antagonists*
  • Plasmodium falciparum / drug effects
  • Plasmodium falciparum / genetics*
  • Point Mutation*
  • Polymerase Chain Reaction
  • Proguanil
  • Triazines / pharmacology

Substances

  • Antimalarials
  • Folic Acid Antagonists
  • Triazines
  • cycloguanil
  • Proguanil