Bilateral gonadoblastoma with chromosomal aberration

Obstet Gynecol. 1977 Jul;50(1 Suppl):35s-38s.


A case is presented of a patient with bilateral gonadoblastoma characterized by primary amenorrhea and intense, generalized hirsutism. The physical examination showed somatic stigmas compatible with gonadal dysgenesis. Pneumopelvigraphy showed a uterus and hypoplastic gonads; no microcalcification was seen. Negative sex chromatin in buccal mucosal cells and a 46, XXr/46,XXp-q-45,X karyotypic constitution was found.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Dysgerminoma / diagnosis
  • Dysgerminoma / genetics*
  • Dysgerminoma / pathology
  • Female
  • Gonads / pathology
  • Humans
  • Karyotyping
  • Mosaicism*
  • Turner Syndrome / diagnosis
  • Turner Syndrome / genetics*
  • Turner Syndrome / pathology