Shear field mapping in actin networks by using magnetic tweezers

Eur Biophys J. 1996;24(5):348-53. doi: 10.1007/BF00180376.

Abstract

An improved magnetic bead microrheometer based on phase contrast microscopy allowing high resolution measurements of local deformations within macromolecular network is applied to study local viscoelastic properties of cross-linked actin networks. By embedding nonmagnetic colloidal beads as probes into the networks, the spatial variation of the strain field within cross-linked actin networks can be mapped. Moreover, the Poisson ratio and shear modulus can be measured locally.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Actins / chemistry*
  • Colloids
  • Elasticity
  • Electrochemistry
  • Electromagnetic Phenomena
  • Gels
  • Poisson Distribution
  • Rheology / methods*
  • Viscosity

Substances

  • Actins
  • Colloids
  • Gels