Chlorpropamide-induced thrombocytopenia

Postgrad Med J. 1977 Feb;53(616):87-8. doi: 10.1136/pgmj.53.616.87.

Abstract

Thrombocytopenia is a rare complication of chlorpropamide therapy. An immunological mechanism is generally held responsible, but has never previously been proved. In the present case the existence of such a mechanism has been established.

Publication types

  • Case Reports

MeSH terms

  • Antibodies / analysis
  • Blood Platelets / immunology
  • Chlorpropamide / adverse effects*
  • Chlorpropamide / immunology
  • Coombs Test
  • Female
  • Humans
  • Middle Aged
  • Thrombocytopenia / chemically induced*
  • Thrombocytopenia / immunology

Substances

  • Antibodies
  • Chlorpropamide