A phase I study of an adeno-associated virus-CFTR gene vector in adult CF patients with mild lung disease

Hum Gene Ther. 1996 Jun 10;7(9):1145-59. doi: 10.1089/hum.1996.7.9-1145.
No abstract available

Publication types

  • Clinical Trial
  • Clinical Trial, Phase I
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Cell Line
  • Clinical Protocols
  • Cystic Fibrosis / complications
  • Cystic Fibrosis / therapy*
  • Cystic Fibrosis Transmembrane Conductance Regulator / genetics*
  • Dependovirus / genetics*
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Genetic Therapy* / adverse effects
  • Genetic Vectors*
  • Humans
  • Lung Diseases / etiology
  • Lung Diseases / therapy*
  • Macaca mulatta
  • Rabbits
  • Risk Assessment

Substances

  • CFTR protein, human
  • Cystic Fibrosis Transmembrane Conductance Regulator