Cloning and sequencing of a cDNA encoding the mouse brain-type cannabinoid receptor protein

DNA Seq. 1995;5(6):385-8. doi: 10.3109/10425179509020870.

Abstract

Mouse brain-type cannabinoid receptor (CB1) cDNA was cloned and sequenced. Comparison to rat and human CB1 sequences showed extensive homology (>96%) both at the nucleotide and protein levels implicating the importance of this protein in mammalian brain physiology.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Brain / metabolism*
  • Cannabinoids / metabolism*
  • Cloning, Molecular
  • Conserved Sequence
  • DNA, Complementary / genetics*
  • Humans
  • Mice
  • Mice, Inbred C57BL
  • Molecular Sequence Data
  • Rats
  • Receptors, Cannabinoid
  • Receptors, Drug / genetics*
  • Sequence Homology, Amino Acid
  • Sequence Homology, Nucleic Acid
  • Species Specificity

Substances

  • Cannabinoids
  • DNA, Complementary
  • Receptors, Cannabinoid
  • Receptors, Drug