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Clinical Trial
. 1996 Sep;153(9):1219-21.
doi: 10.1176/ajp.153.9.1219.

Inositol Treatment of Obsessive-Compulsive Disorder

Clinical Trial

Inositol Treatment of Obsessive-Compulsive Disorder

M Fux et al. Am J Psychiatry. .


Objective: Earlier studies reported that inositol, a simple polyol second messenger precursor, was effective in controlled trials for patients with depression and panic. In this study its effectiveness in obsessive-compulsive disorder was investigated.

Method: Thirteen patients with obsessive-compulsive disorder completed a double-blind, controlled crossover trial of 18 g/day of inositol or placebo for 6 weeks each.

Results: The subjects had significantly lower scores on the Yale-Brown Obsessive Compulsive Scale when taking inositol than when taking placebo.

Conclusions: The authors conclude that inositol is effective in depression, panic, and obsessive-compulsive disorder, a spectrum of disorders responsive to selective serotonin reuptake inhibitors.

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