Abstract
The granulin/epithelin protein motif has an unusual structure consisting of a parallel stack of beta-hairpins stapled together by six disulphide bonds. The new structure also contains a folding subdomain shared by small toxins, protease inhibitors as well as the EGF-like protein modules.
Publication types
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Carps
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Granulins
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Intercellular Signaling Peptides and Proteins*
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Magnetic Resonance Spectroscopy
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Molecular Sequence Data
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Protein Structure, Secondary*
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Proteins / chemistry*
Substances
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Granulins
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Intercellular Signaling Peptides and Proteins
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Proteins