Fusobacterium osteomyelitis and pyarthrosis: a classic case of Lemierre's syndrome

J Pediatr Orthop. Jul-Aug 1996;16(4):529-32. doi: 10.1097/00004694-199607000-00022.


Lemierre's syndrome, a systemic anaerobic infection caused by Fusobacterium necrophorum, is characterized by an acute oropharyngeal infection, septic thrombophlebitis of the internal jugular vein, sepsis, and multiple metastatic infections. It commonly leads to septic arthritis and occasionally to osteomyelitis. In the preantibiotic era, this infection was nearly universally fatal. Today it still poses a potentially grave threat to the young patients affected. Prompt recognition with appropriate debridement and antibiotic treatment results in complete recovery in most cases. We report a case of anaerobic septic arthritis and multifocal acute hematogenous osteomyelitis as part of a classic presentation of Lemierre's syndrome.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Arthritis, Infectious / diagnosis
  • Arthritis, Infectious / microbiology*
  • Fusobacterium*
  • Humans
  • Male
  • Osteomyelitis / diagnosis
  • Osteomyelitis / microbiology*
  • Syndrome