Polymyositis and Sjögren's syndrome associated with bronchiolitis obliterans organizing pneumonia

Intern Med. 1996 Mar;35(3):231-5. doi: 10.2169/internalmedicine.35.231.


Bronchiolitis obliterans organizing pneumonia (BOOP) occurred in a 53-year-old woman with well-documented Sjögren's syndrome (SjS) and polymyositis (PM). BOOP has often been reported as a pulmonary manifestation of collagen vascular diseases, mainly rheumatoid arthritis (RA), but the association of BOOP and PM has rarely been documented. A search of the literature showed only 16 case reports of BOOP associated with polymyositis-dermatomyositis (PM-DM). It is interesting that BOOP occurred prior to PM-DM, while it is commonly believed to occur after RA.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Biopsy
  • Cryptogenic Organizing Pneumonia / complications*
  • Cryptogenic Organizing Pneumonia / diagnosis
  • Cryptogenic Organizing Pneumonia / drug therapy
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Middle Aged
  • Muscle, Skeletal / pathology
  • Polymyositis / complications*
  • Polymyositis / diagnosis
  • Polymyositis / drug therapy
  • Prednisolone / therapeutic use
  • Sjogren's Syndrome / complications*
  • Sjogren's Syndrome / diagnosis
  • Sjogren's Syndrome / drug therapy
  • Tomography, X-Ray Computed


  • Glucocorticoids
  • Prednisolone