Magnetic field tomography of cortical and deep processes: examples of "real-time mapping" of averaged and single trial MEG signals

Int J Psychophysiol. 1995 Dec;20(3):161-75. doi: 10.1016/0167-8760(95)00031-3.


Magnetic field tomography (MFT) provides 3-dimensional estimates of brain activity, from non-contact, non-invasive measurements of the magnetic field generated by coherent electrical activity in the brain. MFT analysis of averaged auditory "odd-ball" data show cortical and deep activation, presumably from the amygdala and hippocampus. These results are compared with MFT estimates obtained from a patient who had undergone lobectomy which removed these structures. The variability from subject to subject is confounded by variability between trials for the same subject; the relationship between the averaged and single trials is probed by bi-hemispheric simultaneous measurements performed under the same odd-ball paradigm and by MFT analysis of auditory evoked data and interictal epileptic activity.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acoustic Stimulation
  • Adult
  • Brain / physiology*
  • Brain / physiopathology
  • Cerebral Cortex / physiology*
  • Cerebral Cortex / physiopathology
  • Computer Systems
  • Epilepsy / physiopathology
  • Evoked Potentials, Auditory / physiology
  • Humans
  • Magnetoencephalography* / instrumentation
  • Male
  • Tomography