A simple device for serial blood collection in human subjects and animals

Exp Clin Endocrinol Diabetes. 1995;103(6):398-401. doi: 10.1055/s-0029-1211385.


A simple system for the continuos withdrawal of blood and the serial collection of blood samples in human subjects and experimental animals is described. It consists of heparin-coated tubing, a connector attached to an indwelling cannula that allows flushing of the i.v. catheter, a peristaltic pump and a fraction collector and an alarm system which is activated when blood flow through the system is interrupted. It can be assembled from parts available in every laboratory or hospital.

MeSH terms

  • Animals
  • Blood Specimen Collection / instrumentation*
  • Catheters, Indwelling
  • Gonadotropin-Releasing Hormone
  • Heparin
  • Humans
  • Kinetics
  • Luteinizing Hormone / blood
  • Periodicity
  • Pituitary Hormones / blood*
  • Sheep


  • Pituitary Hormones
  • Gonadotropin-Releasing Hormone
  • Luteinizing Hormone
  • Heparin