Caveolae and caveolins

Curr Opin Cell Biol. 1996 Aug;8(4):542-8. doi: 10.1016/s0955-0674(96)80033-0.


In the past year, we have witnessed considerable progress towards an understanding of the workings of caveolae. Highlights include the identification of new caveolin family members, the characterization of VIP21-caveolin as a cholesterol-binding oligomeric protein, and evidence for functional interactions between caveolins and heterotrimeric G proteins. In addition, novel systems for caveolae purification and for studying caveolae biogenesis are starting to reveal insights into the molecular basis of caveolae formation and function.

Publication types

  • Review

MeSH terms

  • Biological Transport
  • Caveolin 1
  • Caveolins*
  • Cell Membrane / physiology*
  • Cell Membrane / ultrastructure
  • Endocytosis
  • Membrane Proteins / classification
  • Membrane Proteins / metabolism*
  • Models, Biological
  • Signal Transduction


  • Caveolin 1
  • Caveolins
  • Membrane Proteins