In vivo and in vitro measurement of CYP2C19 activity

Methods Enzymol. 1996;272:105-14. doi: 10.1016/s0076-6879(96)72013-x.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aryl Hydrocarbon Hydroxylases*
  • Cytochrome P-450 CYP2C19
  • Cytochrome P-450 Enzyme System / analysis*
  • Cytochrome P-450 Enzyme System / genetics
  • Cytochrome P-450 Enzyme System / metabolism
  • Humans
  • In Vitro Techniques
  • Mephenytoin / analogs & derivatives
  • Mephenytoin / chemistry
  • Mephenytoin / metabolism
  • Mephenytoin / urine
  • Mixed Function Oxygenases / analysis*
  • Mixed Function Oxygenases / genetics
  • Mixed Function Oxygenases / metabolism
  • Omeprazole / metabolism
  • Phenotype
  • Polymorphism, Genetic
  • Stereoisomerism
  • Substrate Specificity

Substances

  • 4-hydroxymephenytoin
  • Cytochrome P-450 Enzyme System
  • Mixed Function Oxygenases
  • Aryl Hydrocarbon Hydroxylases
  • CYP2C19 protein, human
  • Cytochrome P-450 CYP2C19
  • Omeprazole
  • Mephenytoin