Immunity to Lyme Disease: Protection, Pathology and Persistence

Curr Opin Immunol. 1996 Aug;8(4):503-9. doi: 10.1016/s0952-7915(96)80038-0.


Persistence of the Lyme disease spirochete, Borrelia burgdorferi, in the presence of an active immune response has been well documented. Evidence from the past year indicates that modulation of surface antigens by the spirochete may be a major mechanism for evading the immune response.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Carrier State / immunology*
  • Carrier State / pathology
  • Erythema Chronicum Migrans / immunology
  • Erythema Chronicum Migrans / pathology
  • Erythema Chronicum Migrans / prevention & control*
  • Humans
  • Immunity, Innate / immunology
  • Lyme Disease / immunology*
  • Lyme Disease / pathology*
  • Lyme Disease / prevention & control
  • Time Factors