Neurogenesis in the insect central nervous system

Curr Opin Neurobiol. 1996 Feb;6(1):18-24. doi: 10.1016/s0959-4388(96)80004-3.


Recent advances provide an increasingly sophisticated understanding of Drosophila CNS development. First, genes have been identified that specify unique neuroblast cell fates. Second, neuroblasts have been found to use a novel mechanism for asymmetric localization of proteins into one daughter cell at mitosis. Third, a gene controlling the choice between glial/neuronal determination has been discovered. And finally, new cell-lineage methods are being used to determine the entire lineage of identified neuroblasts, including axon projections and synaptic contacts.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Central Nervous System / growth & development*
  • Ganglia / physiology
  • Models, Neurological
  • Neurons / physiology*