Channels in transporters

Curr Opin Neurobiol. 1996 Jun;6(3):294-302. doi: 10.1016/s0959-4388(96)80111-5.


Recent electrophysiological investigations of plasma membrane neurotransmitter transporters have shown that carriers can function in ways similar to ion channels. The results of these studies reveal underlying mechanisms not encompassed by classic carrier models and support an emerging view that transporter-mediated ionic currents may contribute to signaling in the nervous system.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amino Acid Transport Systems
  • Animals
  • Biogenic Amines / metabolism
  • Biological Transport
  • Carrier Proteins / chemistry
  • Carrier Proteins / metabolism
  • Carrier Proteins / physiology*
  • Electric Conductivity
  • Electrophysiology
  • Humans
  • Ion Channels / physiology*
  • Ions
  • Mathematics


  • Amino Acid Transport Systems
  • Biogenic Amines
  • Carrier Proteins
  • Ion Channels
  • Ions