Predicting the regioselectivity and stereoselectivity of cytochrome P450-mediated reactions: structural models for bioactivation reactions

Adv Exp Med Biol. 1996:387:355-60. doi: 10.1007/978-1-4757-9480-9_43.

Authors

J P Jones¹, M Shou, K R Korzekwa

Affiliation

¹ Department of Pharmacology, University of Rochester, New York 14642, USA.

PMID: 8794229
DOI: 10.1007/978-1-4757-9480-9_43

No abstract available

Publication types

Review

MeSH terms

Animals
Biotransformation
Cytochrome P-450 Enzyme System / metabolism*
Humans
Models, Structural
Stereoisomerism
Xenobiotics / metabolism
Xenobiotics / pharmacokinetics
Xenobiotics / toxicity

Substances

Xenobiotics
Cytochrome P-450 Enzyme System