Acute angle-closure glaucoma associated with intranasal cocaine abuse

Am J Ophthalmol. 1996 Sep;122(3):425-6. doi: 10.1016/s0002-9394(14)72071-9.


Purpose: We report a case of acute angle-closure glaucoma associated with ipsilateral intranasal cocaine abuse.

Methods: We examined and treated a 55-year-old white man who developed primary angle-closure glaucoma in the right eye shortly after intranasal cocaine abuse.

Results: The patient was successfully treated with Nd:YAG laser peripheral iridotomy on the right eye.

Conclusion: Cocaine causes mydriasis and can induce angle closure in predisposed individuals.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Administration, Intranasal
  • Cocaine* / adverse effects
  • Glaucoma, Angle-Closure / chemically induced
  • Glaucoma, Angle-Closure / etiology*
  • Glaucoma, Angle-Closure / surgery
  • Humans
  • Iris / surgery
  • Laser Therapy
  • Male
  • Middle Aged
  • Mydriasis / chemically induced
  • Mydriasis / surgery
  • Substance-Related Disorders / complications*


  • Cocaine