Systemic anomalies in 77 patients with congenital anophthalmos or microphthalmos

Eye (Lond). 1996;10 ( Pt 3):310-4. doi: 10.1038/eye.1996.65.

Abstract

Congenital anophthalmos and microphthalmos are rare conditions which can have associated pathology in the second eye and/or systemic anomalies. A retrospective review of 77 patients with congenital anophthalmos or microphthalmos seen at Moorfields Eye Hospital over a 13 year period was performed. A detailed description of the ocular and systemic anomalies present in our series of patients is given, and the current understanding of the pathogenesis of congenital anophthalmos and microphthalmos is reviewed.

MeSH terms

  • Abnormalities, Multiple / genetics*
  • Anophthalmos / genetics*
  • Coloboma
  • Female
  • Humans
  • Infant
  • Male
  • Microphthalmos / genetics*
  • Retrospective Studies