Diabetic complications. The importance of glucose control

Endocrinol Metab Clin North Am. 1996 Jun;25(2):243-54. doi: 10.1016/s0889-8529(05)70323-6.


The most important question for clinicians caring for diabetic patients, and for the patient themselves, is whether the risk of complications can be altered by careful control of glycemia. Epidemiologic studies showed a strong relationship between glycemia and diabetic complications, in both type I and type II diabetes. There is a continuous relationship between prevailing glycemia and risk of progression of complications, implying that any improvement in glycemic control is beneficial. The debate of the question has ended--glucose control is important.

Publication types

  • Review

MeSH terms

  • Blood Glucose
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetic Angiopathies / epidemiology*
  • Diabetic Angiopathies / prevention & control*
  • Diabetic Neuropathies / epidemiology*
  • Diabetic Neuropathies / prevention & control*
  • Diabetic Retinopathy / epidemiology*
  • Diabetic Retinopathy / prevention & control*
  • Glycated Hemoglobin A / analysis
  • Humans
  • Hyperglycemia / prevention & control*
  • Risk Factors


  • Blood Glucose
  • Glycated Hemoglobin A