Structural classification of proteins: new superfamilies

Curr Opin Struct Biol. 1996 Jun;6(3):386-94. doi: 10.1016/s0959-440x(96)80059-5.

Abstract

The structural classification of proteins reveals that it is already more likely to find that a new protein structure has similarity to another structure than to find that it has a new fold. Reviewed here are those new superfamilies that include proteins of general interest: Sonic hedgehog, macrophage migration inhibitory factor, nuclear transport factor-2, double stranded RNA binding domain, GroES, the proteasome, new ATP-hydrolyzing ligases and flavoproteins.

Publication types

  • Review

MeSH terms

  • Adenosine Triphosphate / metabolism
  • Alcohol Dehydrogenase / chemistry
  • Carrier Proteins / chemistry
  • Chaperonin 10 / chemistry
  • Flavin-Adenine Dinucleotide / metabolism
  • Hedgehog Proteins
  • Humans
  • Ligases / chemistry
  • Ligases / metabolism
  • Macrophage Migration-Inhibitory Factors / chemistry
  • Models, Molecular
  • Nuclear Proteins / chemistry
  • Nucleocytoplasmic Transport Proteins*
  • Protein Conformation*
  • Proteins / chemistry
  • Proteins / classification*
  • RNA, Double-Stranded / chemistry
  • Trans-Activators*

Substances

  • Carrier Proteins
  • Chaperonin 10
  • Hedgehog Proteins
  • Macrophage Migration-Inhibitory Factors
  • Nuclear Proteins
  • Nucleocytoplasmic Transport Proteins
  • Proteins
  • RNA, Double-Stranded
  • SHH protein, human
  • Trans-Activators
  • Flavin-Adenine Dinucleotide
  • Adenosine Triphosphate
  • Alcohol Dehydrogenase
  • Ligases