The RING finger domain: a recent example of a sequence-structure family
- PMID: 8804826
- DOI: 10.1016/s0959-440x(96)80060-1
The RING finger domain: a recent example of a sequence-structure family
Abstract
In the past 18 months, two RING finger structures have been solved. They represent the first reported structures for this novel zinc-binding sequence motif. Both structures are significantly different from other zinc-binding domains, in terms of both their zinc-ligation scheme and their three-dimensional structures. The RING finger domain appears to be a convenient scaffold which can be altered to provide functional specificity in those proteins that contain the motif.
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