Signalling pathways: jack of all cascades

Curr Biol. 1996 Jan 1;6(1):16-9. doi: 10.1016/s0960-9822(02)00410-4.

Abstract

The transcription factors that bind the c-fos promoter element SRE are targeted by multiple, independent signalling cascades; the identities of these signalling pathways and their modes of activation are being elucidated.

Publication types

  • Review

MeSH terms

  • Animals
  • DNA-Binding Proteins / metabolism*
  • Intracellular Signaling Peptides and Proteins
  • JNK Mitogen-Activated Protein Kinases*
  • MAP Kinase Kinase 4
  • Mitogen-Activated Protein Kinase 9
  • Mitogen-Activated Protein Kinase Kinases*
  • Mitogen-Activated Protein Kinases / metabolism
  • Nuclear Proteins / metabolism*
  • Oncogene Proteins*
  • Protein Kinases / metabolism
  • Protein-Serine-Threonine Kinases / metabolism
  • Proto-Oncogene Proteins / metabolism
  • Proto-Oncogene Proteins c-ets
  • Serum Response Factor
  • Signal Transduction / physiology*
  • Transcription Factors / metabolism
  • ets-Domain Protein Elk-1
  • ets-Domain Protein Elk-4
  • ras Proteins / metabolism

Substances

  • DNA-Binding Proteins
  • Elk3 protein, mouse
  • Intracellular Signaling Peptides and Proteins
  • Nuclear Proteins
  • Oncogene Proteins
  • Proto-Oncogene Proteins
  • Proto-Oncogene Proteins c-ets
  • Serum Response Factor
  • Transcription Factors
  • ets-Domain Protein Elk-1
  • ets-Domain Protein Elk-4
  • Protein Kinases
  • MAP-kinase-activated kinase 2
  • Mitogen-Activated Protein Kinase 9
  • Protein-Serine-Threonine Kinases
  • JNK Mitogen-Activated Protein Kinases
  • Mitogen-Activated Protein Kinases
  • MAP Kinase Kinase 4
  • Mitogen-Activated Protein Kinase Kinases
  • ras Proteins