Molecular mechanisms for focal adhesion assembly through regulation of protein-protein interactions

A P Gilmore; K Burridge

doi:10.1016/s0969-2126(96)00069-x

Molecular mechanisms for focal adhesion assembly through regulation of protein-protein interactions

Structure. 1996 Jun 15;4(6):647-51. doi: 10.1016/s0969-2126(96)00069-x.

Authors

A P Gilmore¹, K Burridge

Affiliation

¹ Department of Cell Biology and Anatomy, University of North Carolina at Chapel Hill 27599, USA.

PMID: 8805551
DOI: 10.1016/s0969-2126(96)00069-x

Abstract

Focal adhesions provide a useful model for studying cell/extracellular matrix interactions and the subsequent cytoskeletal reorganization. Recent advances have suggested potential mechanisms by which cells may regulate focal adhesion assembly following integrin-mediated cell adhesion.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Actins / metabolism
Cell Adhesion Molecules / metabolism
Extracellular Matrix / metabolism*
Fibronectins / metabolism
Focal Adhesion Protein-Tyrosine Kinases
Integrins / metabolism*
Models, Molecular
Protein-Tyrosine Kinases / metabolism

Substances

Actins
Cell Adhesion Molecules
Fibronectins
Integrins
Protein-Tyrosine Kinases
Focal Adhesion Protein-Tyrosine Kinases