Molecular mechanisms for focal adhesion assembly through regulation of protein-protein interactions

Structure. 1996 Jun 15;4(6):647-51. doi: 10.1016/s0969-2126(96)00069-x.

Abstract

Focal adhesions provide a useful model for studying cell/extracellular matrix interactions and the subsequent cytoskeletal reorganization. Recent advances have suggested potential mechanisms by which cells may regulate focal adhesion assembly following integrin-mediated cell adhesion.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Actins / metabolism
  • Cell Adhesion Molecules / metabolism
  • Extracellular Matrix / metabolism*
  • Fibronectins / metabolism
  • Focal Adhesion Protein-Tyrosine Kinases
  • Integrins / metabolism*
  • Models, Molecular
  • Protein-Tyrosine Kinases / metabolism

Substances

  • Actins
  • Cell Adhesion Molecules
  • Fibronectins
  • Integrins
  • Protein-Tyrosine Kinases
  • Focal Adhesion Protein-Tyrosine Kinases