Mucosal T cells and mast cells share common adhesion receptors

Immunol Today. 1996 Feb;17(2):60-3. doi: 10.1016/0167-5699(96)80580-9.


Mast cells and T cells share common homing/adhesion receptors, which suggests that they have evolved to use similar trafficking pathways. Furthermore, these cells have been shown to co-localize in the gastrointestinal mucosa, and it is possible that they act in concert to achieve an immune response. Here, Tracey Smith and John Weis discuss the implications of this potential collaboration.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Adhesion Molecules / immunology
  • Gastric Mucosa / cytology
  • Gastric Mucosa / immunology*
  • Humans
  • Intestinal Mucosa / cytology
  • Intestinal Mucosa / immunology*
  • Mast Cells / cytology
  • Mast Cells / immunology*
  • T-Lymphocytes / cytology
  • T-Lymphocytes / immunology*


  • Cell Adhesion Molecules