DnaSP, DNA sequence polymorphism: an interactive program for estimating population genetics parameters from DNA sequence data

Comput Appl Biosci. 1995 Dec;11(6):621-5. doi: 10.1093/bioinformatics/11.6.621.


DnaSP, DNA sequence polymorphism, is an interactive computer program for the analysis of DNA polymorphism from nucleotide sequence data. The program, addressed to molecular population geneticists, calculates several measures of DNA sequence variation within and between populations, linkage disequilibrium parameters and Tajima's D statistic. The program, which is written in Visual Basic v. 3.0 and runs on an IBM-compatible PC under Windows, can handle a large number of sequences of up to thousands of nucleotides each.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biometry
  • DNA / genetics*
  • Drosophila / genetics
  • Evaluation Studies as Topic
  • Genes, Insect
  • Genetic Variation
  • Genetics, Population
  • Linkage Disequilibrium
  • Polymorphism, Genetic*
  • Sequence Analysis, DNA / methods*
  • Sequence Analysis, DNA / statistics & numerical data
  • Software*


  • DNA