Ring chromosome 4 and Wolf syndrome

Hum Genet. 1977 Jun 10;37(1):87-91. doi: 10.1007/BF00293777.


A 5-day-old male child presenting some features of Wolf syndrome is studied. The analysis of his karyotype by usual techniques showed a ring chromosome of B group. This chromosome was presnt in most of the cells examined. By GTG banding it was identified as a No.4 chromosome, the karyotype being: 46,XY,r(4),(p15 leads to q35). The analysis was completed by familial cytogenetic and dermatoglyphic studies.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple / genetics*
  • Chromosome Aberrations / genetics*
  • Chromosome Disorders
  • Chromosomes, Human, 4-5*
  • Dermatoglyphics
  • Humans
  • Infant, Newborn
  • Karyotyping
  • Male
  • Syndrome