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. 1996 Jun;44(6):1279-81.
doi: 10.1248/cpb.44.1279.

New bioactive monoterpene glycosides from Paeoniae Radix

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New bioactive monoterpene glycosides from Paeoniae Radix

N Murakami et al. Chem Pharm Bull (Tokyo). 1996 Jun.

Abstract

Bioassay-guided separation of MeOH extract of Japanese Paeoniae Radix inhibiting contractile responses of guinea pig ileum stimulated with electric field disclosed a new monoterpene glycoside, 6-O-beta-D-glucopyranosyl-lactinolide (1), as an active constituent together with two new monoterpene glycosides (3 and 4) and two new monoterpenes (2 and 5). Furthermore, 1-O-beta-D-glucopyranosyl-paeonisuffrone (2) was found to inhibit histamine release from rat peritoneal exudate cells induced by antigen-antibody reaction.

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